This study explores how workplace isolation and loneliness affect employee wellbeing, and whether job design or social dynamics can reduce their impact. It finds that feeling disconnected from the organisation has a stronger negative effect on wellbeing than isolation from colleagues. Simply increasing interaction through task design does not improve outcomes. Instead, supportive behaviours between colleagues play a key role in improving wellbeing and can even offset the negative effects of isolation and loneliness. The findings highlight that meaningful, supportive relationships, not just more interaction, are central to creating healthier workplace environments.